Synthetic Biology

A Divergent Class of Arylamine N-Acetyltransferases Catalyzes Convergent Amidative Condensation of Polyketides in Manumycins Biosynthesis
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Xudong Kong
7 views
Application of Engineered NK-92 Cell Extracellular Vesicles in the Treatment of Systemic Lupus Erythematosus
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Xiaowei Dou
9 views
Coordinated Membrane Deformation Driven by a Minimal Set of Spiroplasma MreB Isoforms
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librarian
14 views
Systematic CRISPRi screening reveals genetic modulators of  E. coli  isoprenoid production
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Kimberly Reynolds
12 views
In-situ Target Base Editing Combining with Biosensor-driven Strategy Reveals Critical Single Nucleotide Variants for Enhanced Recombinant Protein Secretion in Pichia pastoris
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Chong Zhang
15 views
Existence and Localization of a Limit Cycle in a Class of Benchmark Biomolecular Oscillators
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Sidhanta Mohanty
13 views
Multicenter preclinical validation of next-generation CAR T cells: a strategy for harmonization, reproducibility, and its feasibility in clinical translation
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librarian
10 views
Expression landscape of heterologous enzymes in Synechocystis sp. PCC 6803
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Elias Englund
16 views
Sequence Design and Phylogenetic Inference with Generative Flow Networks
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librarian
19 views
DNA Protonuclei as Programmable Nuclear Mimics Reveal Environmental Context on Protein Phase Separation
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librarian
18 views
Exploring Chromosomal Position Effects for Predictable Tuning of Metabolic Pathways in Yeast
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Chang Dong
17 views
Automated Knowledge Graph Construction for CAR T Cell Receptor Design via Hybrid Text Mining
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Haomiao Luo
23 views
Maximally Divergent Synonymous Gene Design with SIRIUS
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Stefano Lonardi
17 views
Gain-Scheduled Optogenetic Feedback for Disturbance Rejection in Bacterial Batch Cultures
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librarian
17 views
Surface Display For Phage Assisted Continuous Evolution: A Platform For Evolving / Screening Nanobodies In Prokaryote Systems
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Benjamin Bartelle
23 views
Humanization of the rpb9 locus in fission yeast reveals conserved and divergent roles of rpb9 and human POLR2I
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librarian
26 views
Tuning a light-regulated allosteric switch for enhanced temporal control of protein activity
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librarian
21 views
Receptor-guided AAV Tropism Engineering via MATCH
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librarian
27 views
Mathematical modeling and sensitivity analysis of synNotch-CAR T-cells identify engineering targets for dynamic tunability
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librarian
22 views
BLAST: A blue light-assisted secretion toolkit tunable by reversible protein-protein interactions
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Dongmin Lee
23 views
Turning of (Ph)age: Expanding the therapeutic potential of our viral allies
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librarian
27 views
A CURE for synthetic regulation of gene expression: Rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology
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Arjun Khakhar
26 views
Tardigrade-Derived Strategy for Low-Cost Storage of Cell-Free Expression Lysates
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Henrike Niederholtmeyer
58 views
Lipid-conjugated DNA enables on-demand delivery of lipids and proteins to synthetic cells
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Stefan Vogel
21 views
AlphaFold Database expands to proteome-scale quaternary structures
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Yewon Han
30 views
An expedient, biology-laboratory-compatible method for preparing functional perfluoropolyether fluorosurfactants for droplet microfluidics
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Chase Akins
25 views
Engineering bacterial combinatorial promoters for two-input chemical AND switching
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librarian
32 views