Pharmacology and Toxicology

Kinetics of cortisol and cortisone binding to corticosteroid binding globulin and albumin in vivo
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librarian
1 view
A Nonsteroidal Reversal Agent Inhibits Allopregnanolone Modulation of α1β3δ GABAA Receptors
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Keith Miller
5 views
Slow Dissociation of Nitazenes from the μ-Opioid Receptor Underlies the Challenge of Overdose Reversal
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librarian
7 views
N-3 Polyunsaturated Fatty Acids Ameliorate Post-infarction Cardiac Dysfunction Through Modulation Of Adiponectin-Ceramide Metabolism
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Xiaofei Guo
7 views
Increased utrophin expression in healthy and DMD patient derived myoblasts in response to ERK1/2 and EZH2 inhibitor treatment
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Hannah Gleneadie
10 views
Three nitrogen atoms turn old kinase inhibitors into new targetable remedy
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librarian
15 views
Using Patient iPSC-derived Retinal Pigment Epithelial Cells to Evaluate Differential Susceptibility to MEK Inhibitor-Associated Retinopathy
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librarian
10 views
Impact of Sex on Heroin Intravenous Self-Administration by Heterogeneous Stock Rats
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librarian
15 views
Influence of different pharmaceuticals on the germination and early development of two leafy vegetable species
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librarian
11 views
Pinus sp. leaf extracts exert antileishmanial effects against Leishmania donovani by targeting trypanothione reductase
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librarian
18 views
PROTAC internalization and target degradation require clathrin-mediatedendocytosis
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Hong-Yu Li
20 views
Morphological and Functional Effects of Cytoskeletal and Ion-Channel Agents on the Protoscolex of Echinococcus granulosus sensu lato
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librarian
18 views
Simian Immunodeficiency Virus and Antiretroviral Therapy Impact Rhesus Macaque Brain Lipid Distribution
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librarian
22 views
Changes in dysbiosis and gene expression in the gut of wharf roach (Ligia Spp.) fed with expanded polystyrene
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Seokhyun Lee
24 views
Low cadmium concentrations alter B and T cell responses in Jamaican fruit bats (Artibeus jamaicensis)
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Laura Pulscher
16 views
Nicotine self-administration increases impulsive action: differential effects of nAChR modulators in a Go/No-Go task
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librarian
21 views
In vivo pharmacokinetics and tissue distribution profile of a Wnt/β-catenin pathway-targeting anticancer cassane diterpene isolated from Caesalpinia pulcherrima
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librarian
30 views
Steroid-based Tide Quencher 1 probes enable real-time mapping of novel non-canonical cholesterol sites on the M1 muscarinic receptor
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librarian
27 views
Cirrina: LLM-driven pharmacological reasoning agent enables preclinical CNS drug evaluation
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librarian
21 views
Study comparing characteristics of ademetionine-containing tablets from different countries
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Azadeh Safaei
27 views
Comparative chemical characterisation of chitosans and their impact on growth, faecal consistency and microbiota composition in weaned piglets
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Simona Di Blasio
24 views
Apelin inhibits cyst growth and improves kidney function in mice with polycystic kidney disease
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librarian
22 views
A stapled peptide inhibitor of MDM2 enables pharmacological activation of p53 in zebrafish
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Dilraj Lama
21 views
AI-Enforced Ultra-Large Virtual Screening Discovers Potent CD28 Binders
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librarian
27 views
INVESTIGATION OF ETHYLENE OXIDE GENOTOXICITY DOSE-RESPONSE TO INFORM CANCER RISK ASSESSMENT
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Abby Li
26 views
Molecular Dosimetry of DNA Adducts in Mice Exposed to Ethylene Oxide
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Kun Lu
34 views
An optimized protocol for single-brain isolation of sex-defined pure mouse astrocyte cultures
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librarian
22 views
Integrated evaluation of immune system perturbation using structural, functional and cellular immunotoxicity endpoints in rats
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Vinay Lomash
32 views
Transporter-Mediated Uptake of Microcystin-LR in Human Trophoblasts: Regulation By Oxygen Concentration and Cell Fusion
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librarian
24 views
In vitro investigation and evaluation of the antidiabetic potential of the ethanolic extract of Asparagus racemosus using starch digestion, glucose diffusion, glucose uptake, and DPPH assays
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Md. Sifat Rahman
23 views
Microencapsulated Vaccinium floribundum Kunth extract promotes angiogenesis and attenuates inflammation in in vitro and in vivo models.
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Giulia Biondolillo
21 views
Investigating the nicotinic receptor EAT-2 as a novel target to mitigate plant parasitic nematode infections
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Henry Nvenankeng
26 views