Pharmacology and Toxicology

Consumption of clinically relevant cannabidiol doses during pregnancy alters postnatal behavior in offspring

Consumption of clinically relevant cannabidiol...

Pharmacology and Toxicology
Avatar
librarian
0 views
Single-Shot Design of a Cyclic Peptide Inhibitor of HIV-1 Membrane Fusion with EvoBind

Single-Shot Design of a Cyclic Peptide Inhibit...

Pharmacology and Toxicology
Avatar
librarian
2 views
Development and Validation of a Stem Cell-Based Kidney Organoid Platform for Nephrotoxicity Assessment

Development and Validation of a Stem Cell-Base...

Pharmacology and Toxicology
Avatar
librarian
0 views
Profiling of HCAR1 signaling reveals Gαi/o and Gαs activation without β-arrestin recruitment and the discovery of an allosteric agonist

Profiling of HCAR1 signaling reveals Gαi/o and...

Pharmacology and Toxicology
Avatar
librarian
0 views
Alignment between Duplex Sequencing and transgenic rodent mutation assay data in the assessment of in vivo NDMA-induced mutagenesis

Alignment between Duplex Sequencing and transg...

Pharmacology and Toxicology
Avatar
Anne Ashford
1 view
Early-life PBDE flame retardant exposures cause neurobehavioral alterations in fish that persist into adulthood and vary by sex and route of exposure

Early-life PBDE flame retardant exposures caus...

Pharmacology and Toxicology
Avatar
librarian
2 views
PBDE flame retardant exposure causes neurobehavioral and transcriptional effects in first-generation but not second-generation offspring fish

PBDE flame retardant exposure causes neurobeha...

Pharmacology and Toxicology
Avatar
Andrew Whitehead
3 views
SynVerse: A Framework for Systematic Evaluation of Deep Learning Based Drug Synergy Prediction Models

SynVerse: A Framework for Systematic Evaluatio...

Pharmacology and Toxicology
Avatar
librarian
2 views
GenVS TBDB: An Open AI-Generated andVirtual Screened Small-Molecule Database for Tuberculosis Drug Discovery

GenVS TBDB: An Open AI-Generated andVirtual Sc...

Pharmacology and Toxicology
Avatar
librarian
2 views
Rapid, open-source, and automated quantification of the head twitch response in C57BL/6J mice using DeepLabCut and Simple Behavioral Analysis

Rapid, open-source, and automated quantificati...

Pharmacology and Toxicology
Avatar
Grant Glatfelter
3 views
Cortical reactive microglia activate astrocytes, increasing neurodegeneration in human alcohol use disorder

Cortical reactive microglia activate astrocyte...

Pharmacology and Toxicology
Avatar
Fulton Crews
7 views
Nanotechnology-Driven Synergy: Research Effects of Curcumin Nanosuspension and Fluconazole Combination in Overcoming Azole Resistance in Candida Albicans

Nanotechnology-Driven Synergy: Research Effect...

Pharmacology and Toxicology
Avatar
Cheng Zhang
5 views
Exploring Phage-Staphylococcus aureus Host Dynamics Through Innovative In Vitro Experiment and Pharmacokinetic/pharmacodynamic Modeling

Exploring Phage-Staphylococcus aureus Host Dyn...

Pharmacology and Toxicology
Avatar
librarian
5 views
RSPO2-based peptibodies conjugated with pyrrolobenzodiazepine dimer or camptothecin analogs demonstrate potent anti-tumor activity by targeting the three receptors LGR4/5/6

RSPO2-based peptibodies conjugated with pyrrol...

Pharmacology and Toxicology
Avatar
librarian
5 views
An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

An Enantioselective Chemical Probe for Chikung...

Pharmacology and Toxicology
Avatar
librarian
3 views
Cannabidiol Reduces Oxycodone Self-Administration While Preserving Its Analgesic Efficacy in a Rat Model of Neuropathic Pain

Cannabidiol Reduces Oxycodone Self-Administrat...

Pharmacology and Toxicology
Avatar
librarian
10 views
On-cell Saturation Transfer Difference (STD) NMR on ion channels: characterizing negative allosteric modulator binding interactions of P2X7.

On-cell Saturation Transfer Difference (STD) N...

Pharmacology and Toxicology
Avatar
Serena Monaco
9 views
G protein-coupled receptor 35 (GPR35) stimulation reduces osteoclast activity in primary human bone cells

G protein-coupled receptor 35 (GPR35) stimulat...

Pharmacology and Toxicology
Avatar
librarian
10 views
Peptide-functionalized fluorescent polymeric nanoparticles: polysarcosine length defines stealth properties

Peptide-functionalized fluorescent polymeric n...

Pharmacology and Toxicology
Avatar
librarian
5 views
Exploring Effective Ingredients and Potential Mechanisms of Stem Cell-derived Dendrobium Officinale Extract in Treatment of Allergic Rhinitis

Exploring Effective Ingredients and Potential ...

Pharmacology and Toxicology
Avatar
librarian
6 views
A Lipid Prodrug Strategy Enhances Targeted Protein Degrader CNS Pharmacokinetics

A Lipid Prodrug Strategy Enhances Targeted Pro...

Pharmacology and Toxicology
Avatar
librarian
6 views
Exploring the mechanism of kaji-ichigoside F1 on bacterial pneumonia based on the network pharmacology and transcriptome

Exploring the mechanism of kaji-ichigoside F1 ...

Pharmacology and Toxicology
Avatar
librarian
9 views
Antimuscarinic drugs exert β-arrestin-biased agonism at the muscarinic acetylcholine type 1 receptor

Antimuscarinic drugs exert β-arrestin-biased a...

Pharmacology and Toxicology
Avatar
librarian
11 views
Design of peptide-based PAC1 antagonists combining molecular dynamics simulations and a biologically relevant cell-based assay

Design of peptide-based PAC1 antagonists combi...

Pharmacology and Toxicology
Avatar
librarian
9 views
Evaluation of cytotoxic effects of diverse essential oils on human keratinocytes (HaCaT)

Evaluation of cytotoxic effects of diverse ess...

Pharmacology and Toxicology
Avatar
librarian
10 views
CERIUM OXIDE NANOPARTICLES ATTENUATE THE PRO-ARRHYTHMIC EFFECT OF DIESEL EXHAUST PARTICLES IN ISOLATED RAT HEARTS BY REDUCING OXIDATIVE STRESS.

CERIUM OXIDE NANOPARTICLES ATTENUATE THE PRO-A...

Pharmacology and Toxicology
Avatar
Antonio Rodríguez-Sinovas
15 views
Photodisruption of the inner limiting membrane promotes retinal engraftment of stem-cell derived retinal ganglion cells

Photodisruption of the inner limiting membrane...

Pharmacology and Toxicology
Avatar
Emma De Coster
11 views
DICAR-JP Regulates Ribosome Migration, a New Theory of Mitochondrial Protein Production

DICAR-JP Regulates Ribosome Migration, a New T...

Pharmacology and Toxicology
Avatar
librarian
14 views
Animal product-free formation and cultivation of 3D primary hepatocyte spheroids

Animal product-free formation and cultivation ...

Pharmacology and Toxicology
Avatar
Maria Karlgren
13 views
Accelerated plastic aging in suspension (APAS): A simple, reproducible approach for the generation of model micro- and nanoplastics through simulated environmental forces

Accelerated plastic aging in suspension (APAS)...

Pharmacology and Toxicology
Avatar
librarian
13 views
ArcDFI: Attention Regularization guided by CYP450 Interactions for Predicting Drug-Food Interactions

ArcDFI: Attention Regularization guided by CYP...

Pharmacology and Toxicology
Avatar
Donghyeon Park
12 views
Sevoflurane inhibition of the developmentally expressed neuronal sodium channel Nav1.3

Sevoflurane inhibition of the developmentally ...

Pharmacology and Toxicology
Avatar
Jiaxin Xiang
10 views
Load more