Molecular Biology

DNA Polymerase beta Accelerates Cellular DNA Base Excision Repair by Suppressing Excessive PARP1 Engagement

DNA Polymerase beta Accelerates Cellular DNA B...

Molecular Biology
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Fat body CLOCK restrains innate immunity and maintains survival under dietary stress in Drosophila

Fat body CLOCK restrains innate immunity and m...

Molecular Biology
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CAFE: A Co-folding Approach for Fragment Exploration of Allosteric and Cryptic Binding Sites

CAFE: A Co-folding Approach for Fragment Explo...

Molecular Biology
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Antagonistic regulation of HBZ splicing by hnRNPA1 and hnRNPH1 drives HTLV-1 leukemogenesis.

Antagonistic regulation of HBZ splicing by hnR...

Molecular Biology
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Unmasking Early Renal Fibrosis in Polycystic Kidney Disease Using Noninvasive Precision Molecular MRI of Collagen

Unmasking Early Renal Fibrosis in Polycystic K...

Molecular Biology
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Jenny Yang
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JAK and TYK2 inhibitors differentially modulate interferon/TNF-driven inflammation, stemness and proliferation in the colonic epithelium of ulcerative colitis

JAK and TYK2 inhibitors differentially modulat...

Molecular Biology
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Highly Pathogenic Avian Influenza H5N5 in a Polar Bear and Atlantic Walrus, Svalbard, 2026, with Widespread Seroconversion in Polar Bears

Highly Pathogenic Avian Influenza H5N5 in a Po...

Molecular Biology
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Cross-talk among miRNAs, lncRNAs, and DNA methylation in three coral species reveal conserved epigenetic regulatory architecture

Cross-talk among miRNAs, lncRNAs, and DNA meth...

Molecular Biology
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Characterization of Chromatin-Associated Circular RNAs (cacRNAs)

Characterization of Chromatin-Associated Circu...

Molecular Biology
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NUMonomer enables accurate and scalable nucleic acid structure prediction from primary sequence alone

NUMonomer enables accurate and scalable nuclei...

Molecular Biology
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Toxoplasma TgATG2 works with TgATG9 and TgProp1 to drive autophagic flux for parasite extracellular survival and persistence.

Toxoplasma TgATG2 works with TgATG9 and TgProp...

Molecular Biology
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FOXO/DAF-16 modulates the transcription factor ROR/NHR-23 and inhibits the let-7 microRNA to maintain multipotency during dauer

FOXO/DAF-16 modulates the transcription factor...

Molecular Biology
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John Kim
3 views
Age-dependent Structural Reorganization of the Human Plasma Proteome

Age-dependent Structural Reorganization of the...

Molecular Biology
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A targeted mass-spectrometry plasma proteome for simultaneous multi-disease screening

A targeted mass-spectrometry plasma proteome f...

Molecular Biology
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ORC binding to Heterochromatin Protein 1 through intrinsically disordered regions is required for heterochromatin structure and function

ORC binding to Heterochromatin Protein 1 throu...

Molecular Biology
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Michael Botchan
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Analytical Validation of Automated DNA Isolation from Meat Matrices for High-Quality PCR-Based Food Authentication

Analytical Validation of Automated DNA Isolati...

Molecular Biology
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Yulia Dewi
9 views
Stressor identity shapes plasma proteomic and metabolic responses in humans

Stressor identity shapes plasma proteomic and ...

Molecular Biology
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Tim Ebert
5 views
Structure-guided targeting of the GATAD2A-CHD4 interaction within the MBD2-NuRD complex results in high levels of HbF in adult erythroid cells

Structure-guided targeting of the GATAD2A-CHD4...

Molecular Biology
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David Williams
7 views
The Structure of Escherichia coli MscL and its dimer formation in Nanodiscs

The Structure of Escherichia coli MscL and its...

Molecular Biology
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Bettina Böttcher
15 views
Nuclear acetyl-CoA production by acetyl-CoA synthetase enables dynamic histone acetylation and gene expression in Plasmodium falciparum

Nuclear acetyl-CoA production by acetyl-CoA sy...

Molecular Biology
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12 views
Human 28S rRNA analysed by state-of-the-art oligonucleotide mass spectrometry: benchmarking current capabilities and a call to action for MS-Seq

Human 28S rRNA analysed by state-of-the-art ol...

Molecular Biology
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8 views
Hybrid Tetramers of Wild-Type and Amyloidogenic H88R Transthyretin Challenge the Monomer Paradigm

Hybrid Tetramers of Wild-Type and Amyloidogeni...

Molecular Biology
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Dóra Menyhárd
10 views
Intranucleolar Invasion of Cajal Body Remnants Suppresses Ribosomal Biogenesis in cis and Telomerase Functions in trans

Intranucleolar Invasion of Cajal Body Remnants...

Molecular Biology
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Lu Chen
10 views
Structural tuning of native type V fimbriae shapes mechanical specialization in Porphyromonas gingivalis

Structural tuning of native type V fimbriae sh...

Molecular Biology
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MTERF1 loss buffers against pathogenic mtDNA deletions through transcriptional regulation

MTERF1 loss buffers against pathogenic mtDNA d...

Molecular Biology
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Tamar Kavlashvili
8 views
The Disease Gene THAP12 is a Transcriptional Regulator of Mitochondrial ETC Complex I

The Disease Gene THAP12 is a Transcriptional R...

Molecular Biology
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Optogenetic decoupling of ODC inhibition and degradation reveals a requirement of polyamine oscillation for cell cycle progression

Optogenetic decoupling of ODC inhibition and d...

Molecular Biology
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11 views
DNA catenation is essential for Sister Chromatid Cohesion

DNA catenation is essential for Sister Chromat...

Molecular Biology
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Madhusudhan Srinivasan
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A long-hidden prevalent PCR artifact and its application in DNA library screening

A long-hidden prevalent PCR artifact and its a...

Molecular Biology
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librarian
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Overlapping upstream ORFs repress translation and expand proteome diversity in Arabidopsis

Overlapping upstream ORFs repress translation ...

Molecular Biology
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Systematic Development of a Compact Genome-Editing Tool Leveraging the TAM-Independent DNA Nuclease TasR in Bacillus subtilis

Systematic Development of a Compact Genome-Edi...

Molecular Biology
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The novel HP1a interactor Clump/CG30403 safeguards transposon silencing and reproductive resilience in the Drosophila ovary

The novel HP1a interactor Clump/CG30403 safegu...

Molecular Biology
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