Cancer Biology

Sialylated CD43 is a glyco-immune checkpoint for macrophage phagocytosis

Sialylated CD43 is a glyco-immune checkpoint f...

Cancer Biology
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Todd Golub
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Anti-CSF-1R therapy with combined immuno- chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched Triple Negative Breast Cancers

Anti-CSF-1R therapy with combined immuno- chem...

Cancer Biology
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librarian
0 views
Follistatin-like protein 1 interacts with programmed cell death 4 to promote vascular mimicry in hepatocellular carcinoma by activating the PI3K/AKT/mTOR signaling pathway

Follistatin-like protein 1 interacts with prog...

Cancer Biology
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librarian
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Binding of extracellular vesicles to stretched von Willebrand factor promotes platelet activation

Binding of extracellular vesicles to stretched...

Cancer Biology
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librarian
4 views
Gap scheduling of a PARP inhibitor and nanoparticle TOP1 agent combination avoids synergistic bone marrow toxicity

Gap scheduling of a PARP inhibitor and nanopar...

Cancer Biology
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Mark O'Connor
1 view
Inhibition of MLLT1 limits growth of MLL-AF4 leukaemias without killing healthy haematopoietic stem cells

Inhibition of MLLT1 limits growth of MLL-AF4 l...

Cancer Biology
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Adam Wilkinson
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High-Sensitive Spatial Proteomics for Pancreatic Cancer Progression Analysis

High-Sensitive Spatial Proteomics for Pancreat...

Cancer Biology
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Jongmin Woo
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The Liver-Enriched Long Non-Coding RNA FAM99A Suppresses Tumorigenesis through Negative Regulation of Protein Synthesis

The Liver-Enriched Long Non-Coding RNA FAM99A ...

Cancer Biology
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librarian
2 views
A Characterization of the Immune Cells in Immunocompetent and Immunodeficient Mice with Orthotopic Brain Tumors.

A Characterization of the Immune Cells in Immu...

Cancer Biology
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librarian
1 view
Reprogramming breast cancer cells to breast cancer stem cell-like by the POU1F1 transcription factor

Reprogramming breast cancer cells to breast ca...

Cancer Biology
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Roman Perez-Fernandez
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Integrated single cell spatial multi-omics landscape of WHO grades 2-4 diffuse gliomas identifies locoregional metabolomic regulators of glioma growth

Integrated single cell spatial multi-omics lan...

Cancer Biology
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librarian
0 views
Lamin A/C Deficiency Drives Genomic Instability and Poor Survival in Small-Cell Lung Cancer through Increased R-loop Accumulation

Lamin A/C Deficiency Drives Genomic Instabilit...

Cancer Biology
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librarian
4 views
Phenotypic and Functional Characterization of Oncohistone Mutations in Breast Cancers

Phenotypic and Functional Characterization of ...

Cancer Biology
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librarian
2 views
NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress

NF2 loss malignantly transforms human pancreat...

Cancer Biology
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Pei Wang
2 views
A structure-based modelling approach identifies effective drug combinations for RAS-mutant acute myeloid leukemia

A structure-based modelling approach identifie...

Cancer Biology
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Jonathan Bond
3 views
Design of combination therapeutics from protein response to drugs in ovarian cancer cells

Design of combination therapeutics from protei...

Cancer Biology
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librarian
2 views
NNMT is a biomarker of prostate cancer cells with a mesenchymal phenotype and induces sensitivity to metabolic agents

NNMT is a biomarker of prostate cancer cells w...

Cancer Biology
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librarian
3 views
Cancer-like fragmentomic characteristics of somatic variants in cell-free DNA

Cancer-like fragmentomic characteristics of so...

Cancer Biology
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librarian
4 views
Netrin-1 regulates colorectal cancer stem cell self-renewal via a TFF3 dependent paracrine survival mechanism

Netrin-1 regulates colorectal cancer stem cell...

Cancer Biology
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librarian
3 views
Unmatched cell line collections are not optimal for identification of PARP inhibitor response and drug synergies

Unmatched cell line collections are not optima...

Cancer Biology
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librarian
3 views
PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and Tamoxifen in a luminal A breast cancer model

PAK1 activation drives divergent resistance me...

Cancer Biology
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librarian
4 views
Comparative Analysis of the Effects of PSPH and PHGDH Inhibitors on Tumor Cell Proliferation

Comparative Analysis of the Effects of PSPH an...

Cancer Biology
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librarian
2 views
Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade

Tumor-specific draining lymph node CD8 T cells...

Cancer Biology
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Jonathan Villena-Vargas
6 views
Dexamethasone-Induced p57-Mediated Quiescence Drives Chemotherapy Resistance in Sonic Hedgehog Medulloblastoma

Dexamethasone-Induced p57-Mediated Quiescence ...

Cancer Biology
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James Purzner
3 views
CISH, a novel intracellular immune checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints

CISH, a novel intracellular immune checkpoint,...

Cancer Biology
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Tom Henley
2 views
Plasma protein biomarkers for the early detection of gastric preneoplasia and cancer: a prospective study

Plasma protein biomarkers for the early detect...

Cancer Biology
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Eliette Touati
3 views
SNX-2112 inhibits the ERBB3high tumor population in Plexiform Neurofibromas

SNX-2112 inhibits the ERBB3high tumor populati...

Cancer Biology
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librarian
3 views
NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer

NOTCH1 Acts as a Tumor Suppressor That Induces...

Cancer Biology
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librarian
8 views
Distinct druggable biological processes in early-onset prostate cancer

Distinct druggable biological processes in ear...

Cancer Biology
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Bissan Al-Lazikani
3 views
Exploiting the CXCR3/CXCL10 pathway to override tumor immune suppression by enhancing immune trafficking and effector cell priming in head and neck squamous cell carcinoma

Exploiting the CXCR3/CXCL10 pathway to overrid...

Cancer Biology
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librarian
2 views
Multi-cellular phenotypic dynamics during the progression of breast tumors

Multi-cellular phenotypic dynamics during the ...

Cancer Biology
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Jean Hausser
3 views
Single-cell transcriptomic analysis of HPV-related multiphenotypic sinonasal carcinoma uncovers MYB-HPV association

Single-cell transcriptomic analysis of HPV-rel...

Cancer Biology
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librarian
3 views
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